The Synthesis, Characterization, Molecular Docking and In Vitro Antitumor Activity of Benzothiazole Aniline (BTA) Conjugated Metal-Salen Complexes as Non-Platinum Chemotherapeutic Agents

• Main Authors: Md. Kamrul Islam (Author), Seongmin Ha (Author), Ah-Rum Baek (Author), Byeong-Woo Yang (Author), Yeoun-Hee Kim (Author), Hyun-Jin Park (Author), Minsup Kim (Author), Sung-Wook Nam (Author), Gang-Ho Lee (Author), Yongmin Chang (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we describe the synthesis, characterization, and in vitro biological evaluation of a series of transition metal complexes containing benzothiazole aniline (BTA). We employed BTA, which is known for its selective anticancer activity, and a salen-type Schiff-based ligand to coordinate several tr...