Development and validation of PBPK models for genistein and daidzein for use in a next-generation risk assessment

Development and validation of PBPK models for genistein and daidzein for use in a next-generation risk assessment

IntroductionAll cosmetic ingredients must be evaluated for their safety to consumers. In the absence of in vivo data, systemic concentrations of ingredients can be predicted using Physiologically based Pharmacokinetic (PBPK) models. However, more examples are needed to demonstrate how they can be va...

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Main Authors: A. Najjar (Author), D. Lange (Author), C. Géniès (Author), J. Kuehnl (Author), A. Zifle (Author), C. Jacques (Author), E. Fabian (Author), N. Hewitt (Author), A. Schepky (Author)
Format: Book
Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
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3rd Floor Main Library

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