Multiple germline sequence variants with potential cancer risk uncovered by exome sequencing in an anatomic lab donor cadaver with multiple cancer lesions

• Main Authors: Jessica Liang (Author), Arben Santo (Author), Peter Samuel (Author), Lin Kang (Author), Katherine Salim (Author), Tiffany Carpenetti (Author), Ramu Anandakrishnan (Author), Pawel Michalak (Author), Harold Garner (Author), Robin T. Varghese (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ovarian cancer is the leading cause of death among gynecological cancers in most developed countries, with many patients developing chemotherapy resistance leaving them with a 5-year survival rate of < 35 %. This dismal overall survival is likely due to the histologic subtype of ovarian carcinoma...