Multiple germline sequence variants with potential cancer risk uncovered by exome sequencing in an anatomic lab donor cadaver with multiple cancer lesions

• Автори: Jessica Liang (Автор), Arben Santo (Автор), Peter Samuel (Автор), Lin Kang (Автор), Katherine Salim (Автор), Tiffany Carpenetti (Автор), Ramu Anandakrishnan (Автор), Pawel Michalak (Автор), Harold Garner (Автор), Robin T. Varghese (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2024-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Ovarian cancer is the leading cause of death among gynecological cancers in most developed countries, with many patients developing chemotherapy resistance leaving them with a 5-year survival rate of < 35 %. This dismal overall survival is likely due to the histologic subtype of ovarian carcinoma...