Intracolic ultrasound molecular imaging: a novel method for assessing colonic tumor necrosis factor-α expression in inflammatory bowel disease

• Main Authors: Xiaoyan Miao (Author), Ren Mao (Author), Yujia You (Author), Huichao Zhou (Author), Chen Qiu (Author), Xuehua Li (Author), Zhihui Chen (Author), Jie Ren (Author), Minhu Chen (Author), Ping Wang (Author), Rongqin Zheng (Author), Tinghui Yin (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background While anti-tumor necrosis factor alpha (TNF-α) therapy has been proven effective in inflammatory bowel disease (IBD), approximately 40% of patients lose the response. Transmembrane TNF-α (mTNF-α) expression in the intestinal mucosa is correlated with therapeutic efficacy, and qua...