Methylglyoxal Enhances Sodium Nitroprusside-Induced Relaxation in Rat Aorta

• Autors principals: Masashi Mukohda (Autor), Hideyuki Yamawaki (Autor), Muneyoshi Okada (Autor), Yukio Hara (Autor)
• Format: Llibre
• Publicat: Elsevier, 2010-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The concentration of methylglyoxal (MGO), a metabolite of glucose, increases in plasma of type II diabetic patients as well as in tissues of hypertensive rats. We have previously shown that MGO inhibited noradrenaline (NA)-induced smooth muscle contraction in rat aorta. However, the effect of MGO on...