Methylglyoxal Enhances Sodium Nitroprusside-Induced Relaxation in Rat Aorta

• Главные авторы: Masashi Mukohda (Автор), Hideyuki Yamawaki (Автор), Muneyoshi Okada (Автор), Yukio Hara (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2010-01-01T00:00:00Z.
• Предметы: article
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The concentration of methylglyoxal (MGO), a metabolite of glucose, increases in plasma of type II diabetic patients as well as in tissues of hypertensive rats. We have previously shown that MGO inhibited noradrenaline (NA)-induced smooth muscle contraction in rat aorta. However, the effect of MGO on...