LC-MS based stability-indicating method for studying the degradation of lonidamine under physical and chemical stress conditions

• প্রধান লেখক: Ankit Kanaiyalal Rochani (Author), Margaret Wheatley (Author), Brian Edward Oeffinger (Author), John Robert Eisenbrey (Author), Gagan Kaushal (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background and purpose: Lonidamine is a hexokinase II inhibitor, works as an anticancer molecule, and is extensively explored in clinical trials. Limited information prevails about the stability-indicating methods which could determine the forced degradation of lonidamine under stressed conditions....