Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish

• Main Authors: Joshua D. Wythe (Author), Michael J. Jurynec (Author), Lisa D. Urness (Author), Christopher A. Jones (Author), M. Khaled Sabeh (Author), Andreas A. Werdich (Author), Mariko Sato (Author), H. Joseph Yost (Author), David J. Grunwald (Author), Calum A. MacRae (Author), Dean Y. Li (Author)
• Format: Book
• Published: The Company of Biologists, 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY The vertebrate heart is one of the first organs to form, and its early function and morphogenesis are crucial for continued embryonic development. Here we analyze the effects of loss of Heart adaptor protein 1 (Hadp1), which we show is required for normal function and morphogenesis of the em...