Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

• Główni autorzy: Robert Szabo (Autor), Cristina Petrișor (Autor), Constantin Bodolea (Autor), Vlad Dobre (Autor), Sebastian Tranca (Autor), Simona Clichici (Autor), Iulia Szabo (Autor), Razvan Marian Melinte (Autor), Teodora Mocan (Autor)
• Format: Książka
• Wydane: MDPI AG, 2023-02-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

COVID-19 produces cytokine-mediated persistent inflammation and is associated with elevated iron stores and low circulating iron. It is believed that central to the pathophysiological mechanism is interleukin 6 and hepcidin. A state of iron overload, termed hyperferritinemia, and inflammatory anemia...