Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage

• Autori principali: Jing eLi (Autore), Charles T. Stier (Autore), Praveen N. Chander (Autore), Vijaya L. Manthati (Autore), John R. Falck (Autore), Mairead A. Carroll (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2014-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Kidney damage is markedly accelerated by high-salt (HS) intake in stroke-prone spontaneously hypertensive rats (SHRSP). Epoxyeicosatrienoic acids (EETs) are epoxygenase products of arachidonic acid which possess vasodepressor, natriuretic and anti-inflammatory activities. We examined whether up-regu...