Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage

• প্রধান লেখক: Jing eLi (লেখক), Charles T. Stier (লেখক), Praveen N. Chander (লেখক), Vijaya L. Manthati (লেখক), John R. Falck (লেখক), Mairead A. Carroll (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2014-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Kidney damage is markedly accelerated by high-salt (HS) intake in stroke-prone spontaneously hypertensive rats (SHRSP). Epoxyeicosatrienoic acids (EETs) are epoxygenase products of arachidonic acid which possess vasodepressor, natriuretic and anti-inflammatory activities. We examined whether up-regu...