Up-Regulation of Intrarenal Renin-Agiotensin System Contributes to Renal Damage in High-Salt Induced Hypertension Rats

• Main Authors: Haiyan Wu (Author), Yaoxian Liang (Author), Yimu Zheng (Author), Qiong Bai (Author), Zheng Zhuang (Author), Lata A (Author), Danxia Zheng (Author), Yue Wang (Author)
• Format: Book
• Published: Karger Publishers, 2014-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: To investigate the change of intrarenal renin-agiotensin system (RAS) and its role in high-salt induced hypertension. Methods: Wistar rats were divided into normal-salt (NS), high-salt diet (HS) and high-salt diet with Losartan group (HS+L), for 6 weeks. Systolic blood pressure (SBP...