pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study

Abstract Despite intensive treatments including temozolomide (TMZ) administration, glioblastoma patient prognosis remains dismal and innovative therapeutic strategies are urgently needed. A systems pharmacology approach was undertaken to investigate TMZ pharmacokinetics‐pharmacodynamics (PK‐PD) inco...

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Bibliographic Details
Main Authors: Angélique Stéphanou (Author), Annabelle Ballesta (Author)
Format: Book
Published: Wiley, 2019-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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