Potent dual block to HIV-1 infection using lentiviral vectors expressing fusion inhibitor peptide mC46- and Vif-resistant APOBEC3G

Gene therapy strategies that effectively inhibit HIV-1 replication are needed to reduce the requirement for lifelong antiviral therapy and potentially achieve a functional cure. We previously designed self-activating lentiviral vectors that efficiently delivered and expressed a Vif-resistant mutant...

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Ngā kaituhi matua: Krista A. Delviks-Frankenberry (Author), Chet R. Ojha (Author), Kip J. Hermann (Author), Wei-Shau Hu (Author), Bruce E. Torbett (Author), Vinay K. Pathak (Author)
Hōputu: Pukapuka
I whakaputaina: Elsevier, 2023-09-01T00:00:00Z.
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