CD39hi identifies an exhausted tumor-reactive CD8+ T cell population associated with tumor progression in human gastric cancer

• Main Authors: Yang Shen (Author), Yuan Qiu (Author), Zhen-quan Duan (Author), Yu-xian Li (Author), Ying Wang (Author), Yuan-yuan Zhang (Author), Bao-hang Zhu (Author), Xiao-hong Yu (Author), Xue-ling Tan (Author), Weisan Chen (Author), Yuan Zhuang (Author), Quan-ming Zou (Author), Dai-yuan Ma (Author), Liu-sheng Peng (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ectonucleotidase CD39 has been regarded as a promising immune checkpoint in solid tumors. However, the expression of CD39 by tumor-infiltrating CD8+ T cells as well as their potential roles and clinical implications in human gastric cancer (GC) remain largely unknown. Here, we found that GC-infi...