CD39hi identifies an exhausted tumor-reactive CD8+ T cell population associated with tumor progression in human gastric cancer

• Principais autores: Yang Shen (Autor), Yuan Qiu (Autor), Zhen-quan Duan (Autor), Yu-xian Li (Autor), Ying Wang (Autor), Yuan-yuan Zhang (Autor), Bao-hang Zhu (Autor), Xiao-hong Yu (Autor), Xue-ling Tan (Autor), Weisan Chen (Autor), Yuan Zhuang (Autor), Quan-ming Zou (Autor), Dai-yuan Ma (Autor), Liu-sheng Peng (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2024-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The ectonucleotidase CD39 has been regarded as a promising immune checkpoint in solid tumors. However, the expression of CD39 by tumor-infiltrating CD8+ T cells as well as their potential roles and clinical implications in human gastric cancer (GC) remain largely unknown. Here, we found that GC-infi...