Programmed myofibre necrosis in critical illness acquired muscle wasting

• Main Authors: Sunil Patel (Author), Thomas Francis (Author), Raghini Rajaram (Author), Rhodri Handslip (Author), Sharon Mumby (Author), Danielle E. Bear (Author), Rahul Padhke (Author), Nicholas Hart (Author), Hugh Montgomery (Author), Masao Takata (Author), Stephen D.R. Harridge (Author), Brijesh V. Patel (Author), Zudin Puthucheary (Author)
• Format: Book
• Published: Wiley, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Acute skeletal muscle wasting during critical illness is common and causes significant morbidity and functional limitation. Myofibre necrosis is a major histological finding but is often considered an unprogrammed by‐product of muscle inflammation. This study sought to evaluate i...