Exosomal Transmission of MicroRNA from HCV Replicating Cells Stimulates Transdifferentiation in Hepatic Stellate Cells

The mechanism by which hepatitis C virus (HCV) causes fibrosis and other chronic liver diseases remains poorly understood. Previously, we observed that HCV infection induces microRNA-192 (miR-192) expression, which in turn upregulates transforming growth factor β1 (TGF-β1) in hepatocytes. In this st...

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Main Authors: Ji Hyun Kim (Author), Chang Ho Lee (Author), Seong-Wook Lee (Author)
Format: Bog
Udgivet: Elsevier, 2019-03-01T00:00:00Z.
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