Efficacy, Safety, and Retention Rate of Extended-Release Divalproex Versus Conventional Delayed-Release Divalproex: A Meta-Analysis of Controlled Clinical Trials

• Autores principales: Chen Qi Zhang (Autor), Hong Yan Li (Autor), Yong Wan (Autor), Xue Yang Bai (Autor), Lu Gan (Autor), Juan Wang (Autor), Hong Bin Sun (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Purpose: A novel once-daily divalproex-extended release (ER) dose formulation has been developed; this formulation prolongs the therapeutic serum levels of the drug, compared with the twice-daily conventional divalproex-delayed release (DR) formulation. This study aimed to systematically examine and...