Glycine Transporter Blockade Ameliorates Motor Ataxia in a Mouse Model of Spinocerebellar Atrophy

• 主要な著者: Mitsuo Tanabe (著者), Tomoharu Nakano (著者), Motoko Honda (著者), Hideki Ono (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2009-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Ataxic movement, the common major symptom of spinocerebellar atrophy, has been considered to involve impaired glutamatergic excitatory neurotransmission in the cerebellum. Considering the therapeutic importance of ataxia control, we assessed the effectiveness of increasing the extracellular concentr...