Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen

• Main Authors: Jordi Rodon (Author), Jordana Muñoz-Basagoiti (Author), Daniel Perez-Zsolt (Author), Marc Noguera-Julian (Author), Roger Paredes (Author), Lourdes Mateu (Author), Carles Quiñones (Author), Carles Perez (Author), Itziar Erkizia (Author), Ignacio Blanco (Author), Alfonso Valencia (Author), Víctor Guallar (Author), Jorge Carrillo (Author), Julià Blanco (Author), Joaquim Segalés (Author), Bonaventura Clotet (Author), Júlia Vergara-Alert (Author), Nuria Izquierdo-Useros (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an urgent need to identify therapeutics for the treatment of Coronavirus disease 2019 (COVID-19). Although different antivirals are given for the clinical management of SARS-CoV-2 infection, their efficacy is still under evaluation. Here, we have screened existing drugs approved for human u...