Synthesis and Biological Evaluation of a Series of Novel 1-(3-((6-Fluoropyridin-3-yl)oxy)propyl)piperazines as Dopamine/Serotonin Receptor Agonists

• Váldodahkkit: Xin-Li Du (Dahkki), Yan-Na Ni (Dahkki), Jiang-Rong Ji (Dahkki), Ze-Hong Wan (Dahkki), Zhi-Jing Hu (Dahkki), Yu-Qiang Ge (Dahkki), Jian-Qi Li (Dahkki), Guan Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Georg Thieme Verlag KG, 2022-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Evidence suggested that the use of partial dopamine D2/D3 receptor agonists may be a better choice for the treatment of Parkinson's disease (PD), and the stimulation of 5-HT1A receptors (mainly via nondopaminergic mechanisms) alleviates motor and nonmotor disorders of PD, implying that...