Up-regulation of CB1 cannabinoid receptors located at glutamatergic terminals in the medial prefrontal cortex of the obese Zucker rat

• Main Authors: Leyre Echeazarra (Author), Sergio Barrondo (Author), Gontzal García del Caño (Author), Itziar Bonilla-Del Río (Author), Jon Egaña-Huguet (Author), Nagore Puente (Author), Xabier Aretxabala (Author), Mario Montaña (Author), Maider López de Jesús (Author), Imanol González-Burguera (Author), Miquel Saumell-Esnaola (Author), María Aránzazu Goicolea (Author), Pedro Grandes (Author), Joan Sallés (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study describes a detailed neuroanatomical distribution map of the cannabinoid type 1 (CB1) receptor, along with the biochemical characterization of the expression and functional coupling to their cognate Gi/o proteins in the medial prefrontal cortex (mPCx) of the obese Zucker rats. The...