In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom

• Main Authors: Line Ledsgaard (Author), Andreas H. Laustsen (Author), Urska Pus (Author), Jack Wade (Author), Pedro Villar (Author), Kim Boddum (Author), Peter Slavny (Author), Edward W. Masters (Author), Ana S. Arias (Author), Saioa Oscoz (Author), Daniel T. Griffiths (Author), Alice M. Luther (Author), Majken Lindholm (Author), Rachael A. Leah (Author), Marie Sofie Møller (Author), Hanif Ali (Author), John McCafferty (Author), Bruno Lomonte (Author), José M. Gutiérrez (Author), Aneesh Karatt-Vellatt (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The monocled cobra (Naja kaouthia) is among the most feared snakes in Southeast Asia due to its toxicity, which is predominantly derived from long-chain α-neurotoxins. The only specific treatment for snakebite envenoming is antivenom based on animal-derived polyclonal antibodies. Despite the lifesav...