Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

• मुख्य लेखकों: Jonathon H. Gralewski (लेखक), Ginell R. Post (लेखक), Frits van Rhee (लेखक), Youzhong Yuan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2018-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Plasma cell myeloma (PCM) is a neoplasm of terminally differentiated B lymphocytes with molecular heterogeneity. Although therapy-related myeloid neoplasms are common in plasma cell myeloma patients after chemotherapy, transdifferentiation of plasma cell myeloma into myeloid neop...