Frataxins Emerge as New Players of the Intracellular Antioxidant Machinery
Frataxin is a mitochondrial protein which deficiency causes Friedreich's ataxia, a cardio-neurodegenerative disease. The lack of frataxin induces the dysregulation of mitochondrial iron homeostasis and oxidative stress, which finally causes the neuronal death. The mechanism through which fratax...
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MDPI AG,
2021-02-01T00:00:00Z.
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