Osteonecrosis of the Jaws (ONJ) after Bisphosphonate Treatment in Patients with Multiple Myeloma: Decreasing ONJ Incidence after Adoption of Preventive Measures

• Main Authors: Gioacchino Catania (Author), Federico Monaco (Author), Giulia Limberti (Author), Manuela Alessio (Author), Iolanda De Martino (Author), Cecilia Barile (Author), Antonella Fasciolo (Author), Anna Baraldi (Author), Marco Ladetto (Author), Vittorio Fusco (Author)
• Format: Book
• Published: MDPI AG, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bisphosphonates (BPs) are administered to Multiple Myeloma (MM) patients with bone lytic lesion. Osteonecrosis of the Jaw (ONJ) is a complication reported since 2003 in patients treated with intravenous (IV) BPs such as zoledronic acid and pamidronate, with 6%-26.3% frequency in early literature ser...