Roles of Na+/H+ Exchanger Type 1 and Intracellular pH in Angiotensin II-Induced Reactive Oxygen Species Generation and Podocyte Apoptosis

• Egile Nagusiak: Ya Liu (Egilea), Hirofumi Hitomi (Egilea), Suwarni Diah (Egilea), Kazushi Deguchi (Egilea), Hirohito Mori (Egilea), Tsutomu Masaki (Egilea), Daisuke Nakano (Egilea), Hiroyuki Kobori (Egilea), Akira Nishiyama (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2013-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A growing body of evidence suggests that podocyte apoptosis is a major cause of decreased podocyte number, which leads to albuminuria and glomerular injury. The aim of this study was to clarify the molecular mechanisms of angiotensin II (Ang II)-induced apoptosis in cultured mouse podocytes. We exam...