PTEN, MMP2, and NF-κB and Regulating MicroRNA-181 Aggravate Insulin Resistance and Progression of Diabetic Nephropathy: A Case-Control Study

• Main Authors: Manoj Khokhar (Author), Purvi Purohit (Author), Sojit Tomo (Author), Riddhi G. Agarwal (Author), Ashita Gadwal (Author), Nitin Kumar Bajpai (Author), Gopal Krishna Bohra (Author), Ravindra Kumar Shukla (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic nephropathy (DN) is characterized by an increase in urinary albumin excretion, diabetic glomerular lesions, and a decline in glomerular filtration rate (GFR). We assessed the expression of phosphatase and tensin homolog (PTEN), nuclear factor kappa-β (NF-κB), matrix metalloproteinase-2 (MMP...