Eugenol and lidocaine inhibit voltage-gated Na+ channels from dorsal root ganglion neurons with different mechanisms

Eugenol (EUG) is a bioactive monoterpenoid used as an analgesic, preservative, and flavoring agent. Our new data show EUG as a voltage-gated Na+ channel (VGSC) inhibitor, comparable but not identical to lidocaine (LID). EUG inhibits both total and only TTX-R voltage-activated Na+ currents (INa) reco...

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Main Authors: Luiz Moreira-Junior (Author), Jose Henrique Leal-Cardoso (Author), Antonio Carlos Cassola (Author), Joao Luis Carvalho- (Author)
Format: Book
Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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