HZ-A-018, a novel inhibitor of Bruton tyrosine kinase, exerts anti-cancer activity and sensitizes 5-FU in gastric cancer cells

• Main Authors: Danjing Liu (Author), Wei Xu (Author), Bin Lin (Author), Cong Ji (Author), Minmin Shen (Author), Shuying Shen (Author), Junjie Ma (Author), Xinglu Zhou (Author), Youyou Yan (Author), Bo Zhang (Author), Nengming Lin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric cancer is the third leading cause of cancer related death worldwide. Due to the complexity and heterogeneity of gastric cancer, the development of targeted drugs is somehow limited, but is urgently needed. Since the expression of Bruton tyrosine kinase (BTK) was significantly associated with...