Safety and Efficacy of the Sirolimus Gel for TSC Patients With Facial Skin Lesions in a Long-Term, Open-Label, Extension, Uncontrolled Clinical Trial

• Main Authors: Mari Wataya-Kaneda (Author), Hiroshi Nagai (Author), Yuuki Ohno (Author), Hiroo Yokozeki (Author), Yasuyuki Fujita (Author), Hironori Niizeki (Author), Kazue Yoshida (Author), Masaaki Ogai (Author), Yuichi Yoshida (Author), Akihiko Asahina (Author), Kazuyoshi Fukai (Author), Chiharu Tateishi (Author), Izumi Hamada (Author), Tatsuro Takahata (Author), Kenji Shimizu (Author), Shigeki Shimasaki (Author), Hiroyuki Murota (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Our previous clinical studies have demonstrated the short-term efficacy and safety of the sirolimus gel for patients with tuberous sclerosis complex (TSC). However, long-term clinical evidence is lacking. Our objective was to assess the safety and efficacy of long-term treatmen...