Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway

• Main Authors: Xuping Shao (Author), Changling Li (Author), Junhui Liang (Author), Li Changzhong (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

AbstractBackground Abnormal stromal-epithelial cell communication is a pathogenic mechanism in endometriosis, and metformin can modulate it. Insulin-like growth factor binding protein-1 (IGFBP1) plays a role in endometriosis, but the exact mechanism is unknown. IGFBP1 is reportedly a downstream targ...