Investigating Structural Property Relationships to Enable Repurposing of Pharmaceuticals as Zinc Ionophores

• Main Authors: Oisín Kavanagh (Author), Robert Elmes (Author), Finbarr O'Sullivan (Author), John Farragher (Author), Shane Robinson (Author), Gavin Walker (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The importance of zinc in biology has gained greater recognition in recent years due to its essential contributions to the function of many endogenous enzymes. Disruption of zinc homeostasis may be useful in treating pathological conditions, such as Alzheimer's, and for antiviral purposes. Desp...