Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease

• Main Authors: Femke C. C. van Rhijn-Brouwer (Author), Bas W. M. van Balkom (Author), Diana A. Papazova (Author), Diënty H. M. Hazenbrink (Author), Anke J. Meijer (Author), Isaac Brete (Author), Vidalmar Briceno (Author), Arjan D. van Zuilen (Author), Raechel J. Toorop (Author), Joost O. Fledderus (Author), Hendrik Gremmels (Author), Marianne C. Verhaar (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Cell-based therapies are being developed to meet the need for curative therapy in chronic kidney disease (CKD). Bone marrow- (BM-) derived mesenchymal stromal cells (MSCs) enhance tissue repair and induce neoangiogenesis through paracrine action of secreted proteins and extracellular ves...