Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative model

• Main Authors: Rency S. Varghese (Author), Yuan Zhou (Author), Megan Barefoot (Author), Yifan Chen (Author), Cristina Di Poto (Author), Abdalla Kara Balla (Author), Everett Oliver (Author), Zaki A. Sherif (Author), Deepak Kumar (Author), Alexander H. Kroemer (Author), Mahlet G. Tadesse (Author), Habtom W. Ressom (Author)
• Format: Book
• Published: BMC, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The established role miRNA-mRNA regulation of gene expression has in oncogenesis highlights the importance of integrating miRNA with downstream mRNA targets. These findings call for investigations aimed at identifying disease-associated miRNA-mRNA pairs. Hierarchical integrative...