Bioisosteric Replacement in the Search for Biologically Active Compounds: Design, Synthesis and Anti-Inflammatory Activity of Novel [1,2,4]triazino[2,3-c]quinazolines

• Main Authors: Oleksandr Grytsak (Author), Kostiantyn Shabelnyk (Author), Hanna Severina (Author), Victor Ryzhenko (Author), Oleksii Voskoboinik (Author), Igor Belenichev (Author), Serhii Kovalenko (Author), Valentyn Oksenych (Author), Oleksandr Kamyshnyi (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background:</b> Designing novel biologically active compounds with anti-inflammatory properties based on condensed quinazolines is a significant area of interest in modern medicinal chemistry. In the present study, we describe the development of promising new bioactive molecules throu...