Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice

• Main Authors: Xiao-feng Wang (Author), Hong-he Xiao (Author), Yu-tong Wu (Author), Liang Kong (Author), Ji-cong Chen (Author), Jing-xian Yang (Author), Xiao-le Hu (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Alzheimer's disease (AD) is the most common dementia worldwide, and there is still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese medicine with multiple neuroprotective effects. In present study, we investigated the effects of thre...