HBXIP blocks myosin-IIA assembly by phosphorylating and interacting with NMHC-IIA in breast cancer metastasis

• Main Authors: Lu Zhang (Author), Xiaolei Zhou (Author), Bowen Liu (Author), Xuhe Shi (Author), Xianmeng Li (Author), Feifei Xu (Author), Xueli Fu (Author), Xue Wang (Author), Kai Ye (Author), Tianzhi Jin (Author), Huimin Sun (Author), Qianqian Li (Author), Weiying Zhang (Author), Lihong Ye (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor metastasis depends on the dynamic balance of the actomyosin cytoskeleton. As a key component of actomyosin filaments, non-muscle myosin-IIA disassembly contributes to tumor cell spreading and migration. However, its regulatory mechanism in tumor migration and invasion is poorly understood. Her...