Mechanism of Apigenin against breast cancer stem cells: network pharmacology and experimental validation

• Main Authors: Mengdie Ou (Author), Zhicheng Deng (Author), Yonghui Shi (Author), Jianxiong He (Author), Zicong Ye (Author), Ming Guo (Author), Guohua Cheng (Author), Junyan Wu (Author), Li Lv (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Apigenin (API), a traditionally sourced flavonoid, is recognized for its anti-neoplastic properties. Despite well-documented effects on tumorigenesis, the detailed therapeutic impact on breast cancer stem cells (BCSCs) and the associated molecular mechanisms are yet to be clarified. The objective of...