Study on sickle cell disease haplotypes reveals the African origin of Amapá's population

• Main Authors: Natália de Morais Castelo (Author), Rafael Espíndola do Nascimento (Author), Artemis Socorro do Nascimento Rodrigues (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction:Sickle cell disease (SCD) is a hereditary, hematologic, multifactorial disease, with high prevalence worldwide; its cause is a mutation in the sixth codon of the beta globin gene (βs).Objective:To identify the haplotypes present in people with SCD in Amapá, and relate them to African d...