Serelaxin Protects H9c2 Cardiac Myoblasts against Hypoxia and Reoxygenation-Induced Damage through Activation of AMP Kinase/Sirtuin1: Further Insight into the Molecular Mechanisms of the Cardioprotection of This Hormone

Serelaxin (RLX), namely the human recombinant Relaxin-2 hormone, protects the heart from ischemia/reperfusion (I/R)-induced damage due to its anti-inflammatory, anti-apoptotic and antioxidant properties. RLX acts by binding to its specific RXFP1 receptor whereby it regulates multiple transduction pa...

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Main Authors: Virginia Zizi (Author), Matteo Becatti (Author), Daniele Bani (Author), Silvia Nistri (Author)
Format: Book
Published: MDPI AG, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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