A machine learning framework for genotyping the structural variations with copy number variant

• मुख्य लेखकों: Tian Zheng (लेखक), Xiaoyan Zhu (लेखक), Xuanping Zhang (लेखक), Zhongmeng Zhao (लेखक), Xin Yi (लेखक), Jiayin Wang (लेखक), Hongle Li (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2020-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Genotyping of structural variation is an important computational problem in next generation sequence data analysis. However, in cancer genomes, the copy number variant(CNV) often coexists with other types of structural variations which significantly reduces the accuracy of the ex...