Dasatinib reverses drug resistance by downregulating MDR1 and Survivin in Burkitt lymphoma cells

• Main Authors: Mitsuki Tabata (Author), Masanobu Tsubaki (Author), Tomoya Takeda (Author), Keisuke Tateishi (Author), Katsumasa Tsurushima (Author), Motohiro Imano (Author), Takao Satou (Author), Toshihiko Ishizaka (Author), Shozo Nishida (Author)
• Format: Book
• Published: BMC, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are urgently required for patients with drug-resistant BL. To investigate th...