Family environment and polygenic risk in the bipolar high‐risk context

• Main Authors: Emma K. Stapp (Author), Janice M. Fullerton (Author), Rashelle J. Musci (Author), Peter P. Zandi (Author), Melvin G. McInnis (Author), Philip B. Mitchell (Author), Leslie A. Hulvershorn (Author), Neera Ghaziuddin (Author), Gloria Roberts (Author), Alessandra G. Ferrera (Author), John I. Nurnberger (Author), Holly C. Wilcox (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The interaction of polygenic risk (PRS) and environmental effects on development of bipolar disorder (BD) is understudied, as are high‐risk offspring perceptions of their family environment (FE). We tested the association of offspring‐perceived FE in interaction with BD‐PRS on li...