Efficient Delivery of Antisense Oligonucleotides Using Bioreducible Lipid Nanoparticles In Vitro and In Vivo

The efficient delivery of antisense oligonucleotides (ASOs) to the targeted cells and organs remains a challenge, in particular, in vivo. Here, we investigated the ability of a library of biodegradable lipid nanoparticles (LNPs) in delivering ASO to both cultured human cells and animal models. We fi...

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Bibliographic Details
Main Authors: Liu Yang (Author), Feihe Ma (Author), Fang Liu (Author), Jinjin Chen (Author), Xuewei Zhao (Author), Qiaobing Xu (Author)
Format: Book
Published: Elsevier, 2020-03-01T00:00:00Z.
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