Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273

• Главные авторы: Tanvi V. Wani (Автор), Silvia Bua (Автор), Pravin S. Khude (Автор), Abdul H. Chowdhary (Автор), Claudiu T. Supuran (Автор), Mrunmayee P. Toraskar (Автор)
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• Опубликовано: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Предметы: article
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A series of novel sulphonamide derivatives was obtained from sulphanilamide which was N4-alkylated with ethyl bromoacetate followed by reaction with hydrazine hydrate. The hydrazide obtained was further reacted with various aromatic aldehydes. The novel sulphonamides were characterised by infrared,...