Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway

• Main Authors: Hongming Zhang (Author), Moyan Liu (Author), Yuyan Zhang (Author), Xiaoyan Li (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Exhausted exercise has been reported to cause the damage of myocardial structure and function in terms of cardiomyocyte apoptosis, oxidative stress, and energy metabolism disturbance. Trimetazidine (TMZ), as an anti-ischemic agent, has been approved to be effective in promoting myocardial energy met...