Data Challenges for Externally Controlled Trials: Viewpoint

• Main Authors: Russanthy Ruthiran Velummailum (Author), Chelsea McKibbon (Author), Darren R Brenner (Author), Elizabeth Ann Stringer (Author), Leeland Ekstrom (Author), Louis Dron (Author)
• Format: Book
• Published: JMIR Publications, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The preferred evidence of a large randomized controlled trial is difficult to adopt in scenarios, such as rare conditions or clinical subgroups with high unmet needs, and evidence from external sources, including real-world data, is being increasingly considered by decision makers. Real-world data o...