Association between DSCAM polymorphisms and non-syndromic Hirschsprung disease in Chinese population

• Main Authors: Yong Wang (Author), Qiuming He (Author), Ruizhong Zhang (Author), Wei Zhong (Author), Deli Zhu (Author), Yan Zhang (Author), Huimin Xia (Author)
• Format: Book
• Published: BMC, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hirschsprung disease (HSCR, aganglionic megacolon) is the most frequent genetic cause of congenital intestinal obstruction. DSCAM was identified as associated to HSCR with Down Syndrome (DS-HSCR) in European population,but failed to replicate in the non-syndromic HSCR patients. W...