Deciphering treatment resistance in metastatic colorectal cancer: roles of drug transports, EGFR mutations, and HGF/c-MET signaling

• Main Authors: Najah Albadari (Author), Yang Xie (Author), Wei Li (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

In 2023, colorectal cancer (CRC) is the third most diagnosed malignancy and the third leading cause of cancer death worldwide. At the time of the initial visit, 20% of patients diagnosed with CRC have metastatic CRC (mCRC), and another 25% who present with localized disease will later develop metast...