ABC Transporters and CYP3A4 Mediate Drug Interactions between Enrofloxacin and Salinomycin Leading to Increased Risk of Drug Residues and Resistance

• Main Authors: Min Chen (Author), Yujuan Yang (Author), Yupeng Ying (Author), Jiamin Huang (Author), Mengyuan Sun (Author), Mian Hong (Author), Haizhen Wang (Author), Shuyu Xie (Author), Dongmei Chen (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enrofloxacin (ENR) is one of the most common drugs used in poultry production to treat bacterial diseases, and there is a high risk of drug interactions (DDIs) between polyether anticoccidial drugs added to poultry feed over time. This may affect the efficacy of antibiotics or lead to toxicity, posi...