Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn trialResearch in context

• मुख्य लेखकों: Israel S. Maia (लेखक), Aline Marcadenti (लेखक), Viviane C. Veiga (लेखक), Tamiris A. Miranda (लेखक), Samara P.C. Gomes (लेखक), Mariana B.S. Carollo (लेखक), Karina L. Negrelli (लेखक), Jackeline O. Gomes (लेखक), Lucas Tramujas (लेखक), Erlon O. Abreu-Silva (लेखक), Glauco A. Westphal (लेखक), Ruthy P. Fernandes (लेखक), Jacques G.A. Horta (लेखक), Deborah C. Oliveira (लेखक), Uri A.P. Flato (लेखक), Ricardo C.R. Paoliello (लेखक), Camilo Fernandes (लेखक), Cássio L. Zandonai (लेखक), Juliana C. Coelho (लेखक), Waldemar C. Barros (लेखक), Juliana C. Lemos (लेखक), Renata S. Bolan (लेखक), Marcela M. Dutra (लेखक), Otavio C.E. Gebara (लेखक), Ana T.A. Lopes (लेखक), Meton S. Alencar Filho (लेखक), Jussara A. Arraes (लेखक), Victor A. Hamamoto (लेखक), Mauro E. Hernandes (लेखक), Nicole A. Golin (लेखक), Tiago M. Santos (लेखक), Renato H.N. Santos (लेखक), Lucas P. Damiani (लेखक), Fernando G. Zampieri (लेखक), João Gesto (लेखक), Flávia R. Machado (लेखक), Régis G. Rosa (लेखक), Luciano C.P. Azevedo (लेखक), Alvaro Avezum (लेखक), Renato D. Lopes (लेखक), Thiago M.L. Souza (लेखक), Otávio Berwanger (लेखक), Alexandre B. Cavalcanti (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Summary: Background: Repurposed drugs for treatment of new onset disease may be an effective therapeutic shortcut. We aimed to evaluate the efficacy of repurposed antivirals compared to placebo in lowering SARS-CoV2 viral load of COVID-19 patients. Methods: REVOLUTIOn is a randomised, parallel, blin...